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Ever, some differences between the 3 are basic: a table has been created to illustrate the major differences. An obvious proviso is that extensive data are available on Viagra (more than 20 million men treated, more than 1100 peer-reviewed articles as of Feb. & 8217;03), but only limited data on Cialis and Levitra. Drs. Gresser and Gleiter from the U. Tubingen in Germany have compared the three drugs via literature review (Eur. J. Med. Res. 7:435, 2002) In brief, efficacy is approximately 70% with all 3 drugs. The side effect profile is similar among the 3 drugs, except that blue discoloration of vision (overlap with PDE-6 in the retina) is seen only with Viagra (<0.5%) and muscle aches only with Cialis (~5%). Otherwise, vasodilatory side effects (headaches, nasal congestion, flushing) are common with all, but are mild, and only rarely cause men to drop out of clinical trials (2-3% quit rate). All 3 will carry a contra-indication in men using organic nitrates. Otherwise, the long ha cialis levitra


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cialis levitra vs Ly in 1983 when British physiologist Giles Brindley cialis levitra vs, Ph.D. dropped his trousers and demonstrated to a shocked AUA audience his phentolamine-induced erection. The drug Brindley injected into his penis was a non-specific vasodilator cialis levitra vs, an alpha-blocking agent cialis levitra vs, and the mechanism of action was clearly corporal smooth muscle relaxation. The effect that Brindley discovered cialis levitra vs, established the fundamentals for the later development of specific cialis levitra vs, safe cialis levitra vs, orally-effective drug therapies cialis levitra vs, ie cialis levitra vs, PDE-5 inhibitors. PDE Inhibition and Smooth Muscle Relaxation Phosphodiesterase (PDE) is an enzyme that causes breakdown of cyclic GMP cialis levitra vs, which is the direct intracellular mediator in the cialis levitra vs.

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