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M.D., affiliated with U.C.L.A., and author of the following programs: Mastering Stress and Depression, MasteringMyLife, and MasteringFood. Paxil vs. Effexor or Wellbutrin Forum: The Mental Health Forum Topic: Depression Subject: Paxil vs. Effexor or Wellbutrin From ToPostnikkrtz03 28 2001.My boyfriend has been taking Paxil for about 2 years now. About 4 months again he visited his doctor and he took his dosage from 25 to 75mg. He went to a new doctor 2 weeks ago who but him on Effexor instead of the Paxil. I am wondering if the Effexor has the same sexual side effects as the Paxil did and if it does are they as strong as the Paxil. Also is Wellbutrin a worthy sub for these two drugs or is it not as potent because I has heard that most people don't suffer any sexual side effects from it.Forum-M.D.-RG03 30 2001nikkrtzThe side effects of each of these medications varies so much that it is hard to predict but when sexual side effects occur it is very common to switch in exactly this way. The first two medications are usually used before wellbutrin because they are generally considered more potent. cerulean03 29 2001C2 .I took paxil for almost 2 years and didn't ever quite feel like it completely did the trick. It did lower libido also. I was switched to Wellbutrin..... which again didn't seem to quite do the trick..... I didn't notice any real change in libido (I'm female though, side effects are likely different for men) I just started taking effexor.... Don't know a thing about it really, only been taking it for a week, and don't notice a change...... Wish you and bf well. G | Physical side effects of paxil | 20mg paxil | Zoloft paxil | Paxil quit | Paxil 20mg | Depression paxil | Cr dose paxil | [ Phentermine ]