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Viagra. 2.6.STABLE5), 1.0 knsq5.knams.wikimedia.org:80 (squid 2.6.STABLE5) Connection: close Sildenafil - Wikipedia, the free encyclopedia ** ** Sildenafil From Wikipedia, the free encyclopedia (Redirected from Viagra) Jump to: navigation, search Sildenafil Systematic (IUPAC) name 1- 4-ethoxy-3-(6,7-dihydro-1-methyl- 7-oxo-3-propyl-1H-pyrazolo 4,3-d pyrimidin-5-yl) phenylsulfonyl -4-methylpiperazine citrate Identifiers CAS number 171599-83-0 ATC code G04BE03 PubChem 5281023 DrugBank APRD00556 Chemical data Formula C22H30N6O4S ยท C6H8O7 Mol. weight base: 474.6 g mol salt: 666.7 g mol SMILES O=S(=O)(N1CCN(C)CC1)c4cc(C=2NC(=O) c3n(C)nc(CCC)c3N=2)c(OCC)cc4 Pharmacokinetic data Bioavailability & 160;? Metabolism & 160;? Half life 3-4h Excretion & 160;? Therapeutic considerations Pregnancy cat. N A Legal status Rx only POM Routes Oral Sildenafil citrate, sold under the names Viagra, Revatio and generically under various other names, is a drug used to treat male erectile dysfunction (impotence) and viagra
 

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Pulmonary arterial hypertension (PAH), developed by the pharmaceutical company Pfizer. Viagra pills are blue and diamond-shaped with the words "Pfizer" on one side, and "VGR xx" (where xx stands for "25", "50" or "100", the dose of that pill in milligrams) on the other. Its primary competitors on the market are tadalafil (Cialis), and vardenafil (Levitra). Contents 1 History 2 Mechanism of action 3 Dosage and price 4 Contraindications 5 Side effects 6 Other uses 6.1 Pulmonary hypertension 6.2 Raynaud's phenomenon 7 Drug abuses 7.1 Aphrodisiac 7.2 Recreational use 8 Chemical Synthesis 9 See also 10 Notes 11 External links edit History Sildenafil (compound UK-92,480) was synthesized by a group of pharmaceutical chemists working at Pfizer's Sandwich, Kent research facility. It was initially studied for use in hypertension (high blood pressure) and angina pectoris (a form of ischaemic cardiovascular disease). Phase I clinical trials under the direction of Ian Osterloh suggested that the dr viagra


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viagra Dalafil (Cialis) Vardenafil (Levitra) edit Notes ^ Boolell M viagra, Allen MJ viagra, Ballard SA viagra, Gepi-Attee S viagra, Muirhead GJ viagra, Naylor AM viagra, Osterloh IH viagra, Gingell C (1996). "Sildenafil: an orally active type 5 cyclic GMP-specific phosphodiesterase inhibitor for the treatment of penile erectile dysfunction". Int J Impot Res 8 (2): 47โ€“52. PMID 8858389. ^ Terrett viagra, N. K. et al. Sildenafil (Viagra) viagra, a potent and selective inhibitor of Type 5 cGMP phosphodiesterase with utility for the treatment of male erectile dysfunction. Bioorg. Med. Chem. Lett. 1996 viagra, 6 viagra, 1819โ€“1824. ^ Kling J. From hypertension to angina to Viagra. Mod Drug Discov 1998;1:31โ€“38. Fulltext. ^ Bellis viagra, Mary. "Via viagra.

viagra Gra viagra, the patenting of an aphrodisiac." About.com. ^ Cheitlin MD viagra, Hutter AM Jr viagra, Brindis RG viagra, Ganz P viagra, Kaul S viagra, Russell RO Jr viagra, Zusman RM (1999). "ACC AHA expert consensus document. Use of sildenafil (Viagra) in patients with cardiovascular disease. American College of Cardiology American Heart Association". Journal of the American College of Cardiology 33 (1): 273-82. PMID 9935041. ^ Alert for Healthcare Professionals: Sildenafil citrate (marketed as Viagra) (07 2005) ^ Pomeranz HD viagra, Bhavsar AR. "Nonarteritic ischemic optic neuropathy developing soon after use of sildenafil (viagra): a report of seven new cases." J Neuroophthalmol. 2005 Mar;25(1):9-13. PMID 15756125. ^ Egan R viagra, Pomeranz H. "Sildenafil (Viagra) associated anterior ischemic optic neuropathy." Arch Ophthalmol. 2000 Feb;118(2):291-2. PMID 10676804. ^ Pomeranz HD viagra, Smith KH viagra, Hart WM Jr viagra, Egan RA. "Sildenafil-associated nonarteritic anterior ischemic optic neuropathy." Ophthalmology. 2002 Mar;109(3):584-7. PMID 11874765. ^ Cunningham AV viagra, Smith KH. "Anterior ischemic optic neuropathy associated with viagra." J Neuroophthalmol. 2001 Mar;21(1):22-5. PMID 11315976. ^ Boshier A viagra, Pambakian N viagra, Shakir SA. "A case of nonarteritic ischemic optic neuropathy (NAION) in a male patient taking sildenafil." Int J Clin Pharmacol Ther. 2002 Sep;40(9):422-3. PMID 12358159. ^ Aka.

viagra 5. ^ Egan R viagra, Pomeranz H. "Sildenafil (Viagra) associated anterior ischemic optic neuropathy." Arch Ophthalmol. 2000 Feb;118(2):291-2. PMID 10676804. ^ Pomeranz HD viagra, Smith KH viagra, Hart WM Jr viagra, Egan RA. "Sildenafil-associated nonarteritic anterior ischemic optic neuropathy." Ophthalmology. 2002 Mar;109(3):584-7. PMID 11874765. ^ Cunningham AV viagra, Smith KH. "Anterior ischemic optic neuropathy associated with viagra." J Neuroophthalmol. 2001 Mar;21(1):22-5. PMID 11315976. ^ Boshier A viagra, Pambakian N viagra, Shakir SA. "A case of nonarteritic ischemic optic neuropathy (NAION) in a male patient taking sildenafil." Int J Clin Pharmacol Ther. 2002 Sep;40(9):422-3. PMID 12358159. ^ Akas.

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